She became one of the most prominent residents of the class, and as of today, she's the only one of them who's left. Over the course of the series, it is revealed that Jo has a pretty heartbreaking backstory. Her biological mother left her at a fire station shortly after giving birth. After that, Jo bounced between foster homes. Eventually, we also learn that Jo's real name is Brooke Stadler, and that she changed her name to hide from her abusive now-ex husband, Paul Stadler.
This foundation gives Jo a strong, hardened exterior. Jo has had a few notable friendships and relationships on the show. Most notable is her connection to Alex. The two start out as friends, which quickly evolves into something more and has been a fairly consistent relationship on the show. While Jo is a capable surgeon, she hasn't done very much to distinguish herself from the pack.
She did become Chief Resident, but that's probably because there weren't any other main characters to give the title to. If anything, the other residents in her class seemed to show more promise initially. Jo hasn't done anything "bad" as a doctor necessarily, but it's the fact that she still hasn't done anything of real note in the medical field that keeps her from being higher on this list.
Like Jo Wilson, Stephanie Edwards was part of season nine's intern class. She became a central member of the Grey's Anatomy cast that culminated with a memorable exit at the end of season thirteen. Things seem to get off to a somewhat rocky start for Stephanie with her relationship with Jackson Avery.
The two become romantically involved, but because there were still tensions between Jackson and April, Stephanie felt like a side character in a needless love triangle. Once the show gave her agency of her own, Stephanie became one of the best residents. She showed an early aptitude for neurosurgery. Amelia Shepherd took Stephanie under her wing, and the two became a fun and skilled surgical duo.
Stephanie shows a fierce determination to help those who can't help themselves. This builds up to her exit from the show, when a fire breaks out in the hospital. Stephanie must try to find a way to save herself and a young child in the hospital. They succeed, but Stephanie suffers severe burns, and she decides to leave the hospital after that.
Had Stephanie stayed, it's likely that she would have probably gotten the Chief Residency spot and become a pretty great surgeon. Unfortunately, her sudden departure stopped that from happening. April Kepner was originally a surgical resident working at Mercy West hospital along with Jackson and a few others.
She is a much more dynamic character than people usually give her credit for, but her surgical skills don't quite match up to the other attendings. She starts out as a devout Christian with a plucky, upbeat personality. However, her road to becoming a trauma surgeon was a bumpy one. April gets fired twice — the first time for inaccurately diagnosing a patient which led to that patient's passing , and the second time for failing her Boards.
Despite that, she still finds her way back to her medical career. Her resolve gets tested at nearly every turn, and she often draws the short end of the stick in situations.
April has endured crises of faith, the death of her first child, and a messy divorce. This all seems to fuel her to become a better surgeon. April has been a lot over the years, and the fact that she is as good of a trauma surgeon as she is says a lot about her as a character.
She may not be the most skilled attending at Grey Sloan, but she is a very dependable doctor who knows what she's doing. George O'Malley was one of the original interns from season one. He was a good-natured guy and a far better surgeon that people realize.
He would have gone much farther, had his career not been tragically cut short. No doctor on Grey's Anatomy really has it easy, but George has a disadvantage early on when he fails his internship test, forcing him to redo his internship year while his friends continue with their residency. However, George does retake the test and passes with flying colors, now more experienced than he was before.
One of the most surprising things about George was his ability to stay calm in high pressure situations. When he and Alex become stuck in an elevator with a patient, George is the one who steps up to the plate to save the patient's life. This proved his aptitude early on as a promising trauma surgeon. Beyond pure skill, though, George was one of the most likable characters, which made him good with his patients. He was kind and compassionate, which helped him to become a well-rounded doctor.
Had George not met an untimely end, he would have probably given Owen and April a run for their money in the Pit. He was arguably one of the best residents ever to appear on the show, and he is a sorely missed doctor. Lexie Grey was Meredith's younger half-sister and a resident at Seattle Grace. She was one of the few people on the show who had meaningful connections with just about every other character, from her sister to Mark Sloan, the love of her life.
Not only that, but her surgical skills showed a ton of promise. A graduate from Harvard Medical School, Lexie quickly proved to be the best out of her internship class, under the supervision of Cristina Yang.
She even took her learning into her own hands by practicing surgical techniques with her fellow interns. While these methods were ultimately ill-advised, it showed what Lexie was willing to do in order to be a better doctor.
Later in her residency, Lexie also proves her skills in neurosurgery by working with Derek Shepherd. She would have become an even better surgeon before meeting an untimely end. With the tragic plane crash at the end of season 8, Lexie never got to reach her full potential as a surgeon. She loses her life in the accident, and this character exit has a huge effect on her fellow doctors and the hospital as a whole.
Her memory lives on as the namesake for Grey Sloan Memorial. Jackson Avery was another doctor from Mercy West, and worked through his residency alongside April. You could say that being a doctor runs in his blood. Jackson comes from a whole family of distinguished doctors, from his grandfather, Harper Avery who the fictional medical award is named after , and his mother, Catherine. His family's background in medicine is part of the reason Jackson became a doctor in the first place.
Despite having pretty big name recognition in the Grey's universe, Jackson always strives to prove himself as a capable doctor. He didn't want his families successes to define him — he wanted to find his own success. To Jackson's credit, he has achieved that goal. While still in residency, Jackson studied under Mark Sloan so he could specialize in Plastics. They became an excellent team together, forming the "Plastics Posse.
Like the other doctors on the show, Jackson has dealt with plenty of struggles, from losing Mark as his mentor, to losing his son Samuel, to his divorce with April. Despite all that, Jackson has become one of the senior members of the hospital, and the Head of Plastic Surgery.
He was a good resident, and today he is a great attending. Maybe that is why the producers did not choose a big name actor to be the one who killed our beloved, McDreamy.
McColl returned to the medical drama for season 16, episode eight, My Shot. He appears again as Dr. Paul Castello, but this time he is on the medical board that is to decide if Meredith Grey Ellen Pompeo gets her medical license back. Half-way through the episode, Meredith can not keep her mouth shut any longer although her lawyer insists she not talk at all. When Dr. Castello tries to question Meredith, she stands up and starts yelling.
When she stops yelling, he collapses into a seizure. Rhimes told E! News in that she and Pompeo decided that as long as Pompeo wants to keep playing Meredith, Rhimes will keep the show alive. World globe An icon of the world globe, indicating different international options.
Get the Insider App. Click here to learn more. A leading-edge research firm focused on digital transformation. Martha Sorren. Every "Grey's Anatomy" episode name is a song title except for one. The series has medical advisors and uses cow organs to make the surgeries look more realistic. Visit Insider's homepage for more stories.
The show's title comes from a real medical textbook. A real hospital is used for some scenes. Only three of the main season-one cast members are still on the show. Bohkee is a scrub nurse in real life. The show takes its medical scenes seriously.
The organs and fake blood are made from some pretty nasty materials. Katherine Heigl rejected her Emmy nomination for her portrayal of Izzie Stevens. A great surgeon who impressed Cristina with her fierce dedication to the job, Stephanie deserved better than to have had her heart broken by Jackson, who left her for April.
Her time at Grey Sloan came to a bittersweet end after she was severely burned in a hospital explosion and chose to travel the world once she recovered. Ranked as one of Seattle Grace's top doctors thanks to his brilliance in the OR, Preston's personality immediately connected with audiences. A grand romance with Cristina helped break down some of his emotional barriers, and he became even more likable as the series gained popularity during its initial seasons.
But the Grey's OG also broke Cristina's heart by leaving her at the altar in his final episode. Washington was fired from Grey's Anatomy following Season 3 for allegedly using a gay slur during an on-set argument with co-star Patrick Dempsey, reportedly in reference to fellow co-star T. Washington's Burke did return to the show for Cristina's final episode in Season 10, offering her his job as head of the hospital he started in Zurich.
We hope to have a fraction of the fortitude Dr. Herman showed when she was diagnosed with a brain tumor. After coming to terms with dying, she was convinced by Arizona and Amelia to undergo surgery to remove it, which left her completely blind. But the resilient doctor bounced back by hooking up with Koracick and declaring blind sex the best sex.
A legend. The great thing about Owen is that he has a big heart. The frustrating thing about Owen is that he doesn't always know what his heart wants. His relationships with Cristina and Amelia crashed and burned in spectacular fashion. In Season 16, it looked like he was finally settling into a sense of normalcy with Teddy and their newborn child, and they planned an at-home wedding.
But after overhearing Teddy having an affair with Tom Koracick via a butt dial, Owen made up an excuse to skip their nuptials. Easily one of the show's most divisive characters, April was a woman of principle who lacked a filter, a trait that often rubbed others the wrong way. A tough-as-nails army doc who can swing it on the battlefield while sporting perfect highlights, Teddy is the real deal.
Her journey to get to a point in her life where she can have the career, the guy, the family, and the friends took many dramatic twists and turns, and that doesn't seem to be letting up anytime soon. From a frustrating back-and-forth with Owen to a fling with Mark to a surprise pregnancy and now an affair, things are never simple for Teddy. Sure, she was messy at times, but Callie always kept things interesting.
Fierce, funny, and endlessly lovable even if Izzie didn't think so , Callie explored her sexuality before ultimately finding her great love with Arizona. She was a force of nature who breathed fresh new life into Grey Sloan after the hospital merger. Enduring everything from a leg amputation to multiple heartbreaks and a fiery romance with Callie, Arizona was a spirited doctor, and we miss her every day that she's been gone.
Behind the unmitigated arrogance and biting one-liners is a decent guy capable of caring about someone other than himself. Tom's best moments are often unexpected, like when he was visibly shaking during Catherine's surgery before quickly pulling it together. He might be an export at putting up a front, but he can also be pretty great when he actually lets his guard down -- and when he isn't having an affair with an engaged woman. There's a reason they call him the Ortho God, and it's not just his swoon-worthy good looks.
His charming personality has us pulling for him to enjoy a happy new beginning with Amelia and their newborn son. A good guy with a heart of gold -- he even cut off his hair to match a patient with the same childhood cancer -- Link is more than meets the eye, and one of our favorite newer additions to the series. Izzie's legacy is haunted by that bizarre ghost sex scene with Denny in Season 5, which unfortunately overshadows the other wonderful things she did on the show.
A dedicated friend who always fought tooth-and-nail for her patients, Izzie had a big heart and brought a special warmth to the show that we still miss all these years later.
In Season 16, we learned —via a letter from Alex Karev Justin Chambers — that she and Alex have twin children, and that the pair had rekindled their romance. While we're happy to see Alex and Izzie build a new life together in Kansas, we hate that it was done at Jo's expense. There's an unwritten rule that doctors must be ridiculously good-looking on Grey's , and this cerebral hunk certainly fits the mold.
Self-assured, almost to a fault, Jackson has had quite the journey since popping up in Season 6, as he's slowly learned that he doesn't have all the answers. After a string of failed relationships, the latest being Maggie and Station 19' s Vic Barrett Doss , we're pulling for him to find a love that lasts. There's no shortage of confident, complicated women on this show, but Catherine is often in a league of her own.
From saving Grey Sloan by replacing Harper Avery's foundation with her own to learning to live with cancer, she's a fighter through-and-through, and we wish we had half of her resilience and determination.
It was pretty much like at first sight with Lexie, whose warm demeanor eventually won over her half-sister, Meredith.
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